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Roles of the clip domains of two protease zymogens in the coagulation cascade in horseshoe crabs

The lipopolysaccharide (LPS)-triggered coagulation cascade in horseshoe crabs comprises three protease zymogens: prochelicerase C (proC), prochelicerase B (proB), and the proclotting enzyme (proCE). The presence of LPS results in autocatalytic activation of proC to α-chelicerase C, which, in turn, a...

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Foilsithe in:J Biol Chem
Main Authors: Yamashita, Keisuke, Shibata, Toshio, Takahashi, Toshiaki, Kobayashi, Yuki, Kawabata, Shun-ichiro
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7324516/
https://ncbi.nlm.nih.gov/pubmed/32409575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.012452
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