Microbe-Specific C3b Deposition in the Horseshoe Crab Complement System in a C2/Factor B-Dependent or -Independent Manner

Complement C3 plays an essential role in the opsonization of pathogens in the mammalian complement system, whereas the molecular mechanism underlying C3 activation in invertebrates remains unknown. To understand the molecular mechanism of C3b deposition on microbes, we characterized two types of C2/...

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Bibliografiske detaljer
Main Authors: Tagawa, Keisuke, Yoshihara, Toyoki, Shibata, Toshio, Kitazaki, Kazuki, Endo, Yuichi, Fujita, Teizo, Koshiba, Takumi, Kawabata, Shun-ichiro
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351276/
https://ncbi.nlm.nih.gov/pubmed/22611464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036783
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