Efficient uptake and retention of iron oxide-based nanoparticles in HeLa cells leads to an effective intracellular delivery of doxorubicin

The purpose of this study was to construct and characterize iron oxide nanoparticles (IONP(CO)) for intracellular delivery of the anthracycline doxorubicin (DOX; IONP(DOX)) in order to induce tumor cell inactivation. More than 80% of the loaded drug was released from IONP(DOX) within 24 h (100% at 7...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Popescu, R. C., Savu, D., Dorobantu, I., Vasile, B. S., Hosser, H., Boldeiu, A., Temelie, M., Straticiuc, M., Iancu, D. A., Andronescu, E., Wenz, F., Giordano, F. A., Herskind, C., Veldwijk, M. R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7324358/
https://ncbi.nlm.nih.gov/pubmed/32601333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67207-y
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