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Efficient uptake and retention of iron oxide-based nanoparticles in HeLa cells leads to an effective intracellular delivery of doxorubicin

The purpose of this study was to construct and characterize iron oxide nanoparticles (IONP(CO)) for intracellular delivery of the anthracycline doxorubicin (DOX; IONP(DOX)) in order to induce tumor cell inactivation. More than 80% of the loaded drug was released from IONP(DOX) within 24 h (100% at 7...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Popescu, R. C., Savu, D., Dorobantu, I., Vasile, B. S., Hosser, H., Boldeiu, A., Temelie, M., Straticiuc, M., Iancu, D. A., Andronescu, E., Wenz, F., Giordano, F. A., Herskind, C., Veldwijk, M. R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7324358/
https://ncbi.nlm.nih.gov/pubmed/32601333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67207-y
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