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Enhanced Internalization of Nanoparticles Following Ionizing Radiation Leads to Mitotic Catastrophe in MG-63 Human Osteosarcoma Cells

This study aims to investigate whether ionizing radiation combined with doxorubicin-conjugated iron oxide nanoparticles (NP-DOX) improves the internalization and cytotoxic effects of the nano-carrier-mediated drug delivery in MG-63 human osteosarcoma cells. NP-DOX was designed and synthesized using...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Popescu, Roxana Cristina, Straticiuc, Mihai, Mustăciosu, Cosmin, Temelie, Mihaela, Trușcă, Roxana, Vasile, Bogdan Ștefan, Boldeiu, Adina, Mirea, Dragoş, Andrei, Radu Florin, Cenușă, Constantin, Mogoantă, Laurenţiu, Mogoșanu, George Dan, Andronescu, Ecaterina, Radu, Mihai, Veldwijk, Marlon R., Savu, Diana Iulia
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7583846/
https://ncbi.nlm.nih.gov/pubmed/33007844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21197220
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