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Notch signaling licenses allergic airway inflammation by promoting Th2 cell lymph node egress
Allergic asthma is mediated by Th2 responses to inhaled allergens. Although previous experiments indicated that Notch signaling activates expression of the key Th2 transcription factor Gata3, it remains controversial how Notch promotes allergic airway inflammation. Here we show that T cell–specific...
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| Опубликовано в: : | J Clin Invest |
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| Главные авторы: | , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Clinical Investigation
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7324208/ https://ncbi.nlm.nih.gov/pubmed/32255764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI128310 |
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