Accumbens Neuroimmune Signaling and Dysregulation of Astrocytic Glutamate Transport Underlie Conditioned Nicotine Seeking Behavior

Nicotine self-administration is associated with decreased expression of the glial glutamate transporter (GLT-1) and the cystine-glutamate exchange protein xCT within the nucleus accumbens core (NAcore). N-acetylcysteine (NAC) has been shown to restore these proteins in a rodent model of drug addicti...

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Publié dans:Addict Biol
Auteurs principaux: Namba, Mark D, Kupchik, Yonatan M, Spencer, Sade M, Garcia-Keller, Constanza, Goenaga, Julianna G, Powell, Gregory L, Vicino, Ian A., Hogue, Ian B, Gipson, Cassandra D
Format: Artigo
Langue:Inglês
Publié: 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7323912/
https://ncbi.nlm.nih.gov/pubmed/31330570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/adb.12797
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