Chronic treatment with N‐acetylcysteine decreases extinction responding and reduces cue‐induced nicotine‐seeking

N‐acetylcysteine (NAC), a promising glutamatergic therapeutic agent, has shown some clinical efficacy in reducing nicotine use in humans and has been shown to reverse drug‐induced changes in glutamatergic neurophysiology. In rats, nicotine‐seeking behavior is associated with alterations in glutamate...

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Bibliografski detalji
Izdano u:Physiol Rep
Glavni autori: Powell, Gregory L., Leyrer‐Jackson, Jonna M., Goenaga, Julianna, Namba, Mark D., Piña, Jose, Spencer, Sade, Stankeviciute, Neringa, Schwartz, Danielle, Allen, Nicholas P., Del Franco, Armani P., McClure, Erin A., Olive, Michael Foster, Gipson, Cassandra D.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
Original Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6328917/
https://ncbi.nlm.nih.gov/pubmed/30632301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13958
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