Chronic treatment with N‐acetylcysteine decreases extinction responding and reduces cue‐induced nicotine‐seeking

N‐acetylcysteine (NAC), a promising glutamatergic therapeutic agent, has shown some clinical efficacy in reducing nicotine use in humans and has been shown to reverse drug‐induced changes in glutamatergic neurophysiology. In rats, nicotine‐seeking behavior is associated with alterations in glutamate...

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Dades bibliogràfiques
Publicat a:Physiol Rep
Autors principals: Powell, Gregory L., Leyrer‐Jackson, Jonna M., Goenaga, Julianna, Namba, Mark D., Piña, Jose, Spencer, Sade, Stankeviciute, Neringa, Schwartz, Danielle, Allen, Nicholas P., Del Franco, Armani P., McClure, Erin A., Olive, Michael Foster, Gipson, Cassandra D.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6328917/
https://ncbi.nlm.nih.gov/pubmed/30632301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13958
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