Chronic treatment with N‐acetylcysteine decreases extinction responding and reduces cue‐induced nicotine‐seeking

N‐acetylcysteine (NAC), a promising glutamatergic therapeutic agent, has shown some clinical efficacy in reducing nicotine use in humans and has been shown to reverse drug‐induced changes in glutamatergic neurophysiology. In rats, nicotine‐seeking behavior is associated with alterations in glutamate...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Powell, Gregory L., Leyrer‐Jackson, Jonna M., Goenaga, Julianna, Namba, Mark D., Piña, Jose, Spencer, Sade, Stankeviciute, Neringa, Schwartz, Danielle, Allen, Nicholas P., Del Franco, Armani P., McClure, Erin A., Olive, Michael Foster, Gipson, Cassandra D.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6328917/
https://ncbi.nlm.nih.gov/pubmed/30632301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13958
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