Loss of Plasticity in the D2-Accumbens Pallidal Pathway Promotes Cocaine Seeking

Distinct populations of D1- and D2-dopamine receptor-expressing medium spiny neurons (D1-/D2-MSNs) comprise the nucleus accumbens, and activity in D1-MSNs promotes, whereas activity in D2-MSNs inhibits, motivated behaviors. We used chemogenetics to extend D1-/D2-MSN cell specific regulation to cue-r...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Heinsbroek, Jasper A., Neuhofer, Daniela N., Griffin, William C., Siegel, Griffin S., Bobadilla, Ana-Clara, Kupchik, Yonatan M., Kalivas, Peter W.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2017
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5296778/
https://ncbi.nlm.nih.gov/pubmed/28123013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2659-16.2016
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