Ex vivo drug screening defines novel drug sensitivity patterns for informing personalized therapy in myeloid neoplasms

Precision medicine approaches such as ex vivo drug sensitivity screening (DSS) are appealing to inform rational drug selection in myelodysplastic syndromes (MDSs) and acute myeloid leukemia, given their marked biologic heterogeneity. We evaluated a novel, fully automated ex vivo DSS platform that us...

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Udgivet i:Blood Adv
Main Authors: Spinner, Michael A., Aleshin, Alexey, Santaguida, Marianne T., Schaffert, Steven A., Zehnder, James L., Patterson, A. Scott, Gekas, Christos, Heiser, Diane, Greenberg, Peter L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2020
Fag:
Myeloid Neoplasia
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7322964/
https://ncbi.nlm.nih.gov/pubmed/32569379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020001934
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