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Clinicopathologic and genetic characterization of nonacute NPM1-mutated myeloid neoplasms

NPM1-mutated myeloid neoplasms (NPM1(+) MNs) with <20% blood or bone marrow blasts are rare and have been previously shown in limited case series to exhibit an aggressive clinical course. We assembled the largest cohort of NPM1(+) MN cases to date (n = 45) and compared it with NPM1(−) MN (n = 95)...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Patel, Sanjay S., Ho, Caleb, Ptashkin, Ryan N., Sadigh, Sam, Bagg, Adam, Geyer, Julia T., Xu, Mina L., Prebet, Thomas, Mason, Emily F., Seegmiller, Adam C., Morgan, Elizabeth A., Steensma, David P., Winer, Eric S., Wong, Waihay J., Hasserjian, Robert P., Weinberg, Olga K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6517660/
https://ncbi.nlm.nih.gov/pubmed/31085507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000090
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