Clinicopathologic and genetic characterization of nonacute NPM1-mutated myeloid neoplasms

NPM1-mutated myeloid neoplasms (NPM1(+) MNs) with <20% blood or bone marrow blasts are rare and have been previously shown in limited case series to exhibit an aggressive clinical course. We assembled the largest cohort of NPM1(+) MN cases to date (n = 45) and compared it with NPM1(−) MN (n = 95)...

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Vydáno v:Blood Adv
Hlavní autoři: Patel, Sanjay S., Ho, Caleb, Ptashkin, Ryan N., Sadigh, Sam, Bagg, Adam, Geyer, Julia T., Xu, Mina L., Prebet, Thomas, Mason, Emily F., Seegmiller, Adam C., Morgan, Elizabeth A., Steensma, David P., Winer, Eric S., Wong, Waihay J., Hasserjian, Robert P., Weinberg, Olga K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2019
Témata:
Myeloid Neoplasia
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6517660/
https://ncbi.nlm.nih.gov/pubmed/31085507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000090
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