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Caffeine as a tool for investigating the integration of Cdc25 phosphorylation, activity and ubiquitin-dependent degradation in Schizosaccharomyces pombe

The evolutionarily conserved Cdc25 phosphatase is an essential protein that removes inhibitory phosphorylation moieties on the mitotic regulator Cdc2. Together with the Wee1 kinase, a negative regulator of Cdc2 activity, Cdc25 is thus a central regulator of cell cycle progression in Schizosaccharomy...

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Publicat a:Cell Div
Autors principals: Alao, John P., Sunnerhagen, Per
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7322915/
https://ncbi.nlm.nih.gov/pubmed/32612670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13008-020-00066-1
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