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The evolutionarily conserved ESRE stress response network is activated by ROS and mitochondrial damage

BACKGROUND: Mitochondrial dysfunction causes or contributes to a wide variety of pathologies, including neurodegenerative diseases, cancer, metabolic diseases, and aging. Cells actively surveil a number of mitochondrial readouts to ensure that cellular homeostasis is maintained. RESULTS: In this art...

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Pubblicato in:BMC Biol
Autori principali: Tjahjono, Elissa, McAnena, Aidan P., Kirienko, Natalia V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7322875/
https://ncbi.nlm.nih.gov/pubmed/32600387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-020-00812-5
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