Identification of evolutionarily conserved DNA damage response genes that alter sensitivity to cisplatin

Ovarian, head and neck, and other cancers are commonly treated with cisplatin and other DNA damaging cytotoxic agents. Altered DNA damage response (DDR) contributes to resistance of these tumors to chemotherapies, some targeted therapies, and radiation. DDR involves multiple protein complexes and si...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Gaponova, Anna V., Deneka, Alexander Y., Beck, Tim N., Liu, Hanqing, Andrianov, Gregory, Nikonova, Anna S., Nicolas, Emmanuelle, Einarson, Margret B., Golemis, Erica A., Serebriiskii, Ilya G.
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386675/
https://ncbi.nlm.nih.gov/pubmed/27863405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13353
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