Identification of evolutionarily conserved DNA damage response genes that alter sensitivity to cisplatin

Ovarian, head and neck, and other cancers are commonly treated with cisplatin and other DNA damaging cytotoxic agents. Altered DNA damage response (DDR) contributes to resistance of these tumors to chemotherapies, some targeted therapies, and radiation. DDR involves multiple protein complexes and si...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Gaponova, Anna V., Deneka, Alexander Y., Beck, Tim N., Liu, Hanqing, Andrianov, Gregory, Nikonova, Anna S., Nicolas, Emmanuelle, Einarson, Margret B., Golemis, Erica A., Serebriiskii, Ilya G.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386675/
https://ncbi.nlm.nih.gov/pubmed/27863405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13353
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