Functional interplay of Epstein-Barr virus oncoproteins in a mouse model of B cell lymphomagenesis

Epstein-Barr virus (EBV) is a B cell transforming virus that causes B cell malignancies under conditions of immune suppression. EBV orchestrates B cell transformation through its latent membrane proteins (LMPs) and Epstein-Barr nuclear antigens (EBNAs). We here identify secondary mutations in mouse...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Sommermann, Thomas, Yasuda, Tomoharu, Ronen, Jonathan, Wirtz, Tristan, Weber, Timm, Sack, Ulrike, Caeser, Rebecca, Zhang, Jingwei, Li, Xun, Chu, Van Trung, Jauch, Anna, Unger, Kristian, Hodson, Daniel J., Akalin, Altuna, Rajewsky, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7322082/
https://ncbi.nlm.nih.gov/pubmed/32522871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1921139117
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