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netSmooth: Network-smoothing based imputation for single cell RNA-seq

Single cell RNA-seq (scRNA-seq) experiments suffer from a range of characteristic technical biases, such as dropouts (zero or near zero counts) and high variance. Current analysis methods rely on imputing missing values by various means of local averaging or regression, often amplifying biases inher...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:F1000Res
Prif Awduron: Ronen, Jonathan, Akalin, Altuna
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: F1000 Research Limited 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814748/
https://ncbi.nlm.nih.gov/pubmed/29511531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.13511.3
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