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Methylation-directed glycosylation of chromatin factors represses retrotransposon promoters
The mechanisms by which methylated mammalian promoters are transcriptionally silenced even in the presence of all of the factors required for their expression have long been a major unresolved issue in the field of epigenetics. Repression requires the assembly of a methylation-dependent silencing co...
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Publicado no: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2020
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7322000/ https://ncbi.nlm.nih.gov/pubmed/32522876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1912074117 |
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