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Methylation-directed glycosylation of chromatin factors represses retrotransposon promoters

The mechanisms by which methylated mammalian promoters are transcriptionally silenced even in the presence of all of the factors required for their expression have long been a major unresolved issue in the field of epigenetics. Repression requires the assembly of a methylation-dependent silencing co...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Boulard, Mathieu, Rucli, Sofia, Edwards, John R., Bestor, Timothy H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7322000/
https://ncbi.nlm.nih.gov/pubmed/32522876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1912074117
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