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DNA double-strand breaks promote methylation of histone H3 on lysine 9 and transient formation of repressive chromatin
Dynamic changes in histone modification are critical for regulating DNA double-strand break (DSB) repair. Activation of the Tip60 acetyltransferase by DSBs requires interaction of Tip60 with histone H3 methylated on lysine 9 (H3K9me3). However, how H3K9 methylation is regulated during DSB repair is...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4078803/ https://ncbi.nlm.nih.gov/pubmed/24927542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1403565111 |
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