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Reversible suppression of T cell function in the bone marrow microenvironment of acute myeloid leukemia

Acute myeloid leukemia (AML) is the most common acute leukemia in adults, with approximately four new cases per 100,000 persons per year. Standard treatment for AML consists of induction chemotherapy with remission achieved in 50 to 75% of cases. Unfortunately, most patients will relapse and die fro...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Lamble, Adam J., Kosaka, Yoko, Laderas, Ted, Maffit, Allie, Kaempf, Andy, Brady, Lauren K., Wang, Weiwei, Long, Nicola, Saultz, Jennifer N., Mori, Motomi, Soong, David, LeFave, Clare V., Huang, Fei, Adams, Homer, Loriaux, Marc M., Tognon, Cristina E., Lo, Pierrette, Tyner, Jeffrey W., Fan, Guang, McWeeney, Shannon K., Druker, Brian J., Lind, Evan F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7321988/
https://ncbi.nlm.nih.gov/pubmed/32513686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1916206117
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