CRISPR-Cas13a Inhibits HIV-1 Infection

CRISPR-Cas provides bacteria and archaea with immunity against invading phages and foreign plasmid DNA and has been successfully adapted for gene editing in a variety of species. The class 2 type VI CRISPR-Cas effector Cas13a targets and cleaves RNA, providing protection against RNA phages. Here we...

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Bibliografiske detaljer
Udgivet i:Mol Ther Nucleic Acids
Main Authors: Yin, Lijuan, Zhao, Fei, Sun, Hong, Wang, Zhen, Huang, Yu, Zhu, Weijun, Xu, Fengwen, Mei, Shan, Liu, Xiaoman, Zhang, Di, Wei, Liang, Cen, Shan, Hu, Siqi, Liang, Chen, Guo, Fei
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Gene & Cell Therapy 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7321785/
https://ncbi.nlm.nih.gov/pubmed/32585623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.05.030
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