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Identification of novel key amino acids at the interface of the transmembrane domains of human BST-2 and HIV-1 Vpu

BACKGROUND: BST-2 (bone marrow stromal cell antigen 2) is an interferon-inducible protein that inhibits virus release by tethering viral particles to the cell surface. This antiviral activity of BST-2 is antagonized by HIV-1 accessory protein Vpu. Vpu physically interacts with BST-2 through their mu...

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Detalhes bibliográficos
Main Authors: Pang, Xiaojing, Hu, Siqi, Li, Jian, Xu, Fengwen, Mei, Shan, Zhou, Jinming, Cen, Shan, Jin, Qi, Guo, Fei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751551/
https://ncbi.nlm.nih.gov/pubmed/23919512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-10-84
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