miR-301a Suppression within Fibroblasts Limits the Progression of Fibrosis through the TSC1/mTOR Pathway

Pulmonary fibrosis has been characterized by abnormal proliferation of fibroblasts and massive deposition of the extracellular matrix, which results from a complex interplay of chronic injury and inflammatory responses. MicroRNA-301a (miR-301a) is activated by multiple inflammatory stimulators, cont...

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Gepubliceerd in:Mol Ther Nucleic Acids
Hoofdauteurs: Wang, Jiexuan, Li, Xun, Zhong, Mingtian, Wang, Yansheng, Zou, Liming, Wang, Miaomiao, Gong, Xiaoli, Wang, Xinjie, Zhou, Chengzhi, Ma, Xiaodong, Liu, Ming
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Gene & Cell Therapy 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7321782/
https://ncbi.nlm.nih.gov/pubmed/32585629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.05.027
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