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Conjugation of Doxorubicin to siRNA Through Disulfide-based Self-immolative Linkers

Co-delivery systems of siRNA and chemotherapeutic drugs have been developed as an attractive strategy to optimize the efficacy of chemotherapy towards cancer cells with multidrug resistance. In these typical systems, siRNAs are usually associated to drugs within a carrier but without covalent intera...

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Bibliografski detalji
Izdano u:Molecules
Glavni autori: Gauthier, Florian, Bertrand, Jean-Rémi, Vasseur, Jean-Jacques, Dupouy, Christelle, Debart, Françoise
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7321315/
https://ncbi.nlm.nih.gov/pubmed/32545345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25112714
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