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Aurora-B Promotes Osteosarcoma Cell Growth and Metastasis Through Activation of the NPM1/ERK/NF-κβ/MMPs Axis

PURPOSE: Osteosarcoma (OS) is the most common primary malignant tumor of the bone in young adolescents and children. We explored the underlying mechanism of Aurora-B in promoting OS cell proliferation and metastasis. PATIENT AND METHODS: Bioinformatics was employed to predict the substrate of Aurora...

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Main Authors: Song, Honghai, Zhou, Yang, Peng, Aifen, Liu, Jiaming, Wu, Xin, Chen, Wenzhao, Liu, Zhili
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7320907/
https://ncbi.nlm.nih.gov/pubmed/32606971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S252847
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