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HOPX Is an Epigenetically Inactivated Tumor Suppressor and Overexpression of HOPX Induce Apoptosis and Cell Cycle Arrest in Breast Cancer

BACKGROUND: Evidence has been shown that abnormal DNA methylation plays a vital role in the progression of breast cancer via silencing of gene expression. The results of bisulfite sequencing showed that the methylation status of HOPX in breast cancer tissues was higher than that in normal breast can...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: You, Qinghua, Geng, Yuanyuan, Ye, Huiying, Zhu, Guixiang, Gao, Xiaofang, Zhu, Hongbo
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7320906/
https://ncbi.nlm.nih.gov/pubmed/32606804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S250404
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