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Overexpression of ezrin inactivates NF2 tumor suppressor in glioblastoma

Glioblastoma is a frequent brain malignancy with a dismal prognosis. The molecular changes causing its aggressive phenotype are under investigation. We report that the cytoskeletal-related proteins neurofibromatosis type 2 (NF2) and ezrin have opposite yet interdependent activities in glioblastoma g...

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Bibliografiske detaljer
Main Authors: Morales, Fabiana C., Molina, Jennifer R., Hayashi, Yuho, Georgescu, Maria-Magdalena
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940645/
https://ncbi.nlm.nih.gov/pubmed/20156804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nop060
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