Targeting the overexpressed ROC1 induces G2 cell cycle arrest and apoptosis in esophageal cancer cells

Recent reports showed that regulator of Cullins-1 (ROC1) play an important role in tumor progression in a tumor-specific manner. However, the role and mechanism of ROC1 in esophageal cancer remains elusive. Here we demonstrated that ROC1 was overexpressed in esophageal squamous cell carcinomas, whic...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhang, Jingyang, Li, Shuo, Shang, Zhaoyang, Lin, Shan, Gao, Peng, Zhang, Yi, Hou, Shuaiheng, Mo, Saijun, Cao, Wenbo, Dong, Ziming, Hu, Tao, Chen, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438718/
https://ncbi.nlm.nih.gov/pubmed/28418860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16250
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