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GenMap: ultra-fast computation of genome mappability

MOTIVATION: Computing the uniqueness of k-mers for each position of a genome while allowing for up to e mismatches is computationally challenging. However, it is crucial for many biological applications such as the design of guide RNA for CRISPR experiments. More formally, the uniqueness or (k, e)-m...

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Bibliografiske detaljer
Udgivet i:Bioinformatics
Main Authors: Pockrandt, Christopher, Alzamel, Mai, Iliopoulos, Costas S, Reinert, Knut
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7320602/
https://ncbi.nlm.nih.gov/pubmed/32246826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa222
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