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Genomic dark matter: the reliability of short read mapping illustrated by the genome mappability score

Motivation: Genome resequencing and short read mapping are two of the primary tools of genomics and are used for many important applications. The current state-of-the-art in mapping uses the quality values and mapping quality scores to evaluate the reliability of the mapping. These attributes, howev...

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Detalhes bibliográficos
Main Authors: Lee, Hayan, Schatz, Michael C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413383/
https://ncbi.nlm.nih.gov/pubmed/22668792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts330
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