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Comparative Analysis of Functional Metagenomic Annotation and the Mappability of Short Reads

To assess the functional capacities of microbial communities, including those inhabiting the human body, shotgun metagenomic reads are often aligned to a database of known genes. Such homology-based annotation practices critically rely on the assumption that short reads can map to orthologous genes...

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Hlavní autoři: Carr, Rogan, Borenstein, Elhanan
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4141809/
https://ncbi.nlm.nih.gov/pubmed/25148512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105776
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