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A metabolic pathway for bile acid dehydroxylation by the gut microbiome
The gut microbiota synthesize hundreds of molecules, many of which are known to impact host physiology. Among the most abundant metabolites are the secondary bile acids deoxycholic acid (DCA) and lithocholic acid (LCA), which accumulate at ~500 μM and are known to block C. difficile growth(1), promo...
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| 出版年: | Nature |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7319900/ https://ncbi.nlm.nih.gov/pubmed/32555455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2396-4 |
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