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Ribotype Classification of Clostridioides difficile Isolates Is Not Predictive of the Amino Acid Sequence Diversity of the Toxin Virulence Factors TcdA and TcdB

Clostridioides (Clostridium) difficile is the most commonly recognized cause of infectious diarrhea in healthcare settings. Currently there is no vaccine to prevent initial or recurrent C. difficile infection (CDI). Two large clostridial toxins, TcdA and TcdB, are the primary virulence factors for C...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Microbiol
Prif Awduron: Li, Zhenghui, Lee, Kwok, Rajyaguru, Urvi, Jones, C. Hal, Janezic, Sandra, Rupnik, Maja, Anderson, Annaliesa S., Liberator, Paul
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318873/
https://ncbi.nlm.nih.gov/pubmed/32636819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.01310
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