Ribotype Classification of Clostridioides difficile Isolates Is Not Predictive of the Amino Acid Sequence Diversity of the Toxin Virulence Factors TcdA and TcdB

Clostridioides (Clostridium) difficile is the most commonly recognized cause of infectious diarrhea in healthcare settings. Currently there is no vaccine to prevent initial or recurrent C. difficile infection (CDI). Two large clostridial toxins, TcdA and TcdB, are the primary virulence factors for C...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Microbiol
Auteurs principaux: Li, Zhenghui, Lee, Kwok, Rajyaguru, Urvi, Jones, C. Hal, Janezic, Sandra, Rupnik, Maja, Anderson, Annaliesa S., Liberator, Paul
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
Sujets:
Microbiology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318873/
https://ncbi.nlm.nih.gov/pubmed/32636819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.01310
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