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Stiff‐Stilbene Ligands Target G‐Quadruplex DNA and Exhibit Selective Anticancer and Antiparasitic Activity

G‐quadruplex nucleic acid structures have long been studied as anticancer targets whilst their potential in antiparasitic therapy has only recently been recognized and barely explored. Herein, we report the synthesis, biophysical characterization, and in vitro screening of a series of stiff‐stilbene...

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Dettagli Bibliografici
Pubblicato in:Chemistry
Autori principali: O'Hagan, Michael P., Peñalver, Pablo, Gibson, Rosina S. L., Morales, Juan C., Galan, M. Carmen
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318697/
https://ncbi.nlm.nih.gov/pubmed/32030823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201905753
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