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Stiff‐Stilbene Ligands Target G‐Quadruplex DNA and Exhibit Selective Anticancer and Antiparasitic Activity

G‐quadruplex nucleic acid structures have long been studied as anticancer targets whilst their potential in antiparasitic therapy has only recently been recognized and barely explored. Herein, we report the synthesis, biophysical characterization, and in vitro screening of a series of stiff‐stilbene...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Chemistry
Main Authors: O'Hagan, Michael P., Peñalver, Pablo, Gibson, Rosina S. L., Morales, Juan C., Galan, M. Carmen
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318697/
https://ncbi.nlm.nih.gov/pubmed/32030823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201905753
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