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Stiff‐Stilbene Ligands Target G‐Quadruplex DNA and Exhibit Selective Anticancer and Antiparasitic Activity

G‐quadruplex nucleic acid structures have long been studied as anticancer targets whilst their potential in antiparasitic therapy has only recently been recognized and barely explored. Herein, we report the synthesis, biophysical characterization, and in vitro screening of a series of stiff‐stilbene...

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Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: O'Hagan, Michael P., Peñalver, Pablo, Gibson, Rosina S. L., Morales, Juan C., Galan, M. Carmen
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318697/
https://ncbi.nlm.nih.gov/pubmed/32030823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201905753
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