MiR-34c downregulation leads to SOX4 overexpression and cisplatin resistance in nasopharyngeal carcinoma

BACKGROUND: A major cause of disease-related death in nasopharyngeal carcinoma (NPC) is the development of distant metastasis (DM) despite combination chemoradiotherapy treatment. We previously identified and validated a four microRNA (miRNA) signature that is prognostic for DM. In this study, chara...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Bissey, Pierre-Antoine, Teng, Mona, Law, Jacqueline H., Shi, Wei, Bruce, Jeff P., Petit, Valentin, Tsao, Sai W., Yip, Kenneth W., Liu, Fei-Fei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318489/
https://ncbi.nlm.nih.gov/pubmed/32586280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07081-z
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