Exosomes overexpressing miR-34c inhibit malignant behavior and reverse the radioresistance of nasopharyngeal carcinoma

BACKGROUND: Malignant behavior and radioresistance, which severely limits the efficacy of radiation therapy (RT) in nasopharyngeal carcinoma (NPC), are associated with tumor progression and poor prognosis. Mesenchymal stem cells (MSCs) are used as a therapeutic tool in a variety of tumors. The aim o...

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Veröffentlicht in:J Transl Med
Hauptverfasser: Wan, Fang-Zhu, Chen, Kai-Hua, Sun, Yong-Chu, Chen, Xi-Chan, Liang, Ren-Ba, Chen, Li, Zhu, Xiao-Dong
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6947927/
https://ncbi.nlm.nih.gov/pubmed/31915008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-02203-z
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