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Synthesis of Small‐Molecule Fluorescent Probes for the In Vitro Imaging of Calcium‐Activated Potassium Channel K(Ca)3.1
Small‐molecule probes for the in vitro imaging of K(Ca)3.1 channel‐expressing cells were developed. Senicapoc, showing high affinity and selectivity for the K(Ca)3.1 channels, was chosen as the targeting component. BODIPY dyes 15–20 were synthesized and connected by a Cu(I)‐catalyzed azide–alkyne [3...
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| Wydane w: | Angew Chem Int Ed Engl |
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| Główni autorzy: | , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
John Wiley and Sons Inc.
2020
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7318252/ https://ncbi.nlm.nih.gov/pubmed/32097518 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202001201 |
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