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Synthesis of Small‐Molecule Fluorescent Probes for the In Vitro Imaging of Calcium‐Activated Potassium Channel K(Ca)3.1
Small‐molecule probes for the in vitro imaging of K(Ca)3.1 channel‐expressing cells were developed. Senicapoc, showing high affinity and selectivity for the K(Ca)3.1 channels, was chosen as the targeting component. BODIPY dyes 15–20 were synthesized and connected by a Cu(I)‐catalyzed azide–alkyne [3...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Angew Chem Int Ed Engl |
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| Κύριοι συγγραφείς: | , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
John Wiley and Sons Inc.
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7318252/ https://ncbi.nlm.nih.gov/pubmed/32097518 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202001201 |
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