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Prostate Organoid Cultures as Tools to Translate Genotypes and Mutational Profiles to Pharmacological Responses

Presented here is a protocol to study pharmacodynamics, stem cell potential, and cancer differentiation in prostate epithelial organoids. Prostate organoids are androgen responsive, three-dimensional (3D) cultures grown in a defined medium that resembles the prostatic epithelium. Prostate organoids...

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Podrobná bibliografie
Vydáno v:J Vis Exp
Hlavní autoři: Pappas, Kyrie J., Choi, Danielle, Sawyers, Charles L., Karthaus, Wouter R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318111/
https://ncbi.nlm.nih.gov/pubmed/31710046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/60346
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