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Prostate Organoid Cultures as Tools to Translate Genotypes and Mutational Profiles to Pharmacological Responses

Presented here is a protocol to study pharmacodynamics, stem cell potential, and cancer differentiation in prostate epithelial organoids. Prostate organoids are androgen responsive, three-dimensional (3D) cultures grown in a defined medium that resembles the prostatic epithelium. Prostate organoids...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Pappas, Kyrie J., Choi, Danielle, Sawyers, Charles L., Karthaus, Wouter R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318111/
https://ncbi.nlm.nih.gov/pubmed/31710046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/60346
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