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The Added Value of Longitudinal Imaging for Preclinical In Vivo Efficacy Testing of Therapeutic Compounds against Cerebral Cryptococcosis

Brain infections with Cryptococcus neoformans are associated with significant morbidity and mortality. Cryptococcosis typically presents as meningoencephalitis or fungal mass lesions called cryptococcomas. Despite frequent in vitro discoveries of promising novel antifungals, the clinical need for dr...

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Vanherp, Liesbeth, Poelmans, Jennifer, Hillen, Amy, Janbon, Guilhem, Brock, Matthias, Lagrou, Katrien, Vande Velde, Greetje, Himmelreich, Uwe
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318040/
https://ncbi.nlm.nih.gov/pubmed/32284382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00070-20
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