The Added Value of Longitudinal Imaging for Preclinical In Vivo Efficacy Testing of Therapeutic Compounds against Cerebral Cryptococcosis

Brain infections with Cryptococcus neoformans are associated with significant morbidity and mortality. Cryptococcosis typically presents as meningoencephalitis or fungal mass lesions called cryptococcomas. Despite frequent in vitro discoveries of promising novel antifungals, the clinical need for dr...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Vanherp, Liesbeth, Poelmans, Jennifer, Hillen, Amy, Janbon, Guilhem, Brock, Matthias, Lagrou, Katrien, Vande Velde, Greetje, Himmelreich, Uwe
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2020
Témata:
Experimental Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318040/
https://ncbi.nlm.nih.gov/pubmed/32284382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00070-20
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