The Added Value of Longitudinal Imaging for Preclinical In Vivo Efficacy Testing of Therapeutic Compounds against Cerebral Cryptococcosis

Brain infections with Cryptococcus neoformans are associated with significant morbidity and mortality. Cryptococcosis typically presents as meningoencephalitis or fungal mass lesions called cryptococcomas. Despite frequent in vitro discoveries of promising novel antifungals, the clinical need for dr...

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Enregistré dans:
Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Vanherp, Liesbeth, Poelmans, Jennifer, Hillen, Amy, Janbon, Guilhem, Brock, Matthias, Lagrou, Katrien, Vande Velde, Greetje, Himmelreich, Uwe
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2020
Sujets:
Experimental Therapeutics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318040/
https://ncbi.nlm.nih.gov/pubmed/32284382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00070-20
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