The Added Value of Longitudinal Imaging for Preclinical In Vivo Efficacy Testing of Therapeutic Compounds against Cerebral Cryptococcosis

Brain infections with Cryptococcus neoformans are associated with significant morbidity and mortality. Cryptococcosis typically presents as meningoencephalitis or fungal mass lesions called cryptococcomas. Despite frequent in vitro discoveries of promising novel antifungals, the clinical need for dr...

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Detaylı Bibliyografya
Yayımlandı:Antimicrob Agents Chemother
Asıl Yazarlar: Vanherp, Liesbeth, Poelmans, Jennifer, Hillen, Amy, Janbon, Guilhem, Brock, Matthias, Lagrou, Katrien, Vande Velde, Greetje, Himmelreich, Uwe
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2020
Konular:
Experimental Therapeutics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318040/
https://ncbi.nlm.nih.gov/pubmed/32284382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00070-20
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