The Added Value of Longitudinal Imaging for Preclinical In Vivo Efficacy Testing of Therapeutic Compounds against Cerebral Cryptococcosis

Brain infections with Cryptococcus neoformans are associated with significant morbidity and mortality. Cryptococcosis typically presents as meningoencephalitis or fungal mass lesions called cryptococcomas. Despite frequent in vitro discoveries of promising novel antifungals, the clinical need for dr...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Vanherp, Liesbeth, Poelmans, Jennifer, Hillen, Amy, Janbon, Guilhem, Brock, Matthias, Lagrou, Katrien, Vande Velde, Greetje, Himmelreich, Uwe
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2020
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318040/
https://ncbi.nlm.nih.gov/pubmed/32284382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00070-20
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