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Control of Akt activity and substrate phosphorylation in cells
Protein kinase B/Akt is a serine/threonine kinase that links receptors coupled to the PI3K lipid kinase to cellular anabolic pathways. Its activity in cells is controlled by reversible phosphorylation and an intramolecular lipid‐controlled allosteric switch. In this review, I outline the current pro...
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| Vydáno v: | IUBMB Life |
|---|---|
| Hlavní autor: | |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
John Wiley & Sons, Inc.
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7317883/ https://ncbi.nlm.nih.gov/pubmed/32125765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iub.2264 |
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