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Control of Akt activity and substrate phosphorylation in cells
Protein kinase B/Akt is a serine/threonine kinase that links receptors coupled to the PI3K lipid kinase to cellular anabolic pathways. Its activity in cells is controlled by reversible phosphorylation and an intramolecular lipid‐controlled allosteric switch. In this review, I outline the current pro...
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| Publicado no: | IUBMB Life |
|---|---|
| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley & Sons, Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7317883/ https://ncbi.nlm.nih.gov/pubmed/32125765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iub.2264 |
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