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Control of Akt activity and substrate phosphorylation in cells
Protein kinase B/Akt is a serine/threonine kinase that links receptors coupled to the PI3K lipid kinase to cellular anabolic pathways. Its activity in cells is controlled by reversible phosphorylation and an intramolecular lipid‐controlled allosteric switch. In this review, I outline the current pro...
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| 發表在: | IUBMB Life |
|---|---|
| 主要作者: | |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
John Wiley & Sons, Inc.
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7317883/ https://ncbi.nlm.nih.gov/pubmed/32125765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iub.2264 |
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