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Size‐dependent secretory protein reflux into the cytosol in association with acute endoplasmic reticulum stress

Once secretory proteins have been targeted to the endoplasmic reticulum (ER) lumen, the proteins typically remain partitioned from the cytosol. If the secretory proteins misfold, they can be unfolded and retrotranslocated into the cytosol for destruction by the proteasome by ER‐Associated protein De...

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Detalhes bibliográficos
Publicado no:Traffic
Main Authors: Lajoie, Patrick, Snapp, Erik L.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons A/S 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7317852/
https://ncbi.nlm.nih.gov/pubmed/32246734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tra.12729
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