Chaperone-mediated reflux of secretory proteins to the cytosol during endoplasmic reticulum stress

Diverse perturbations to endoplasmic reticulum (ER) functions compromise the proper folding and structural maturation of secretory proteins. To study secretory pathway physiology during such “ER stress,” we employed an ER-targeted, redox-responsive, green fluorescent protein—eroGFP—that reports on a...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Igbaria, Aeid, Merksamer, Philip I., Trusina, Ala, Tilahun, Firehiwot, Johnson, Jeffrey R., Brandman, Onn, Krogan, Nevan J., Weissman, Jonathan S., Papa, Feroz R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
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PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561268/
https://ncbi.nlm.nih.gov/pubmed/31101715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1904516116
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