Chaperone-mediated reflux of secretory proteins to the cytosol during endoplasmic reticulum stress

Diverse perturbations to endoplasmic reticulum (ER) functions compromise the proper folding and structural maturation of secretory proteins. To study secretory pathway physiology during such “ER stress,” we employed an ER-targeted, redox-responsive, green fluorescent protein—eroGFP—that reports on a...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Igbaria, Aeid, Merksamer, Philip I., Trusina, Ala, Tilahun, Firehiwot, Johnson, Jeffrey R., Brandman, Onn, Krogan, Nevan J., Weissman, Jonathan S., Papa, Feroz R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2019
Konular:
PNAS Plus
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561268/
https://ncbi.nlm.nih.gov/pubmed/31101715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1904516116
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